Psychology of revenge is a psychological tendency to directly damage the interpersonal relationship on university campus, while interpersonal forgiveness is the emotion-focused countermeasure and an effective way to resolve interpersonal conflict. This study concerns about the effect of Health Education on college students’ psychology of revenge and interpersonal forgiveness. Total 1321 college students of 14 universities in 10 cities in China are investigated the psychology of revenge, interpersonal relationship, and the relationship with Health Education with questionnaire survey. The research reveals that Health Education could effectively reduce college students’ psychology of revenge, effectively promote the interpersonal forgiveness, and significantly enhance the negative effects of interpersonal forgiveness on psychology of revenge. Positively promoting college students’ participation in Health Education is an important route to enhance the interpersonal relationship as well as an effective way to construct harmonious university campus.