The study reviews Chinese and international regional innovation capacity and extenics theory, and applies extenics theory to construct a measurement model of regional innovation coordination. It empirically researches 31 Chinese provinces on the coordination of regional innovation in both 2007 and 2015. The research findings indicate that the Industry-University-Research status is not optimistic in China: on the one hand, the coordination abilities of most enterprises are relatively low; and on the other hand, compared with 2007, the proportion of areas with good coordination dropped 10% in 2015. It is thus clear that the effect of adjustments by relevant government departments relating to Industry-University-Research is poor and the coordination of innovation abilities in some provinces are falling rather than rising. Relevant decision-making authorities should take note of this and take more effective measures to promote the coordination of research cooperation and to enhance regional coordination.