This paper aims to explore how three secondary school teachers make sense of multiplication based on their conceptions of multiplication. The framework of supportive and problematic conceptions in making sense of mathematics proposed by Chin (2013) is exemplified in this study. Initially, data were collected through a survey assessment that consists of a set of mathematical tasks. Then follow-up interviews were conducted with these participants. Three secondary school teachers (Jessica, Sarah and Claire – pseudonyms) participated in this study. Findings revealed that the changes of meanings in multiplication have impacted the sense-making of Sarah and Claire. On the other hand, Jessica who sensed these mathematical changes could talk about multiplication sensibly.