This paper focuses on a conversation with Dr. Kenneth Tobin, which took place in June 2009 at The Graduate Center of the City University of New York (CUNY), where he is Presidential Professor in the Urban Education Program. Our purpose was to focus on Ken’s career in science education, and to discuss the past, present, and future of his research interests. During our conversation, we explored the various trajectories of his career, focusing on the ways in which his research has evolved through the years. Further, Ken shared his thoughts on the field of science education, and provided salient advice for early career scholars. This manuscript includes an introductory summary of Ken’s career achievements to this point, a record of our conversation (the audio-recording can be downloaded at the journal’s website) and a list of selected publications that highlight Ken’s key works.